Overview
SCIENTIFIC SCORE
Possibly Effective
Based on 30 Researches
7.2
USERS' SCORE
Good
Based on 2 Reviews
8.3
Supplement Facts
Serving Size: 1 vegan softgel
Amount Per Serving
%DV
Calories
5
_
Total Fat
0.5 g
<1%‡
Microalgae Oil (40% DHA)which typically provides:
500 mg
*
DHA (Docosahexaenoic Acid) [Ω-3]
200 mg
*
Top Medical Research Studies
9
Omega-3s' mixed effects on heart health
We examined the impact of omega-3 fatty acids, often found in fish oil, on heart attack risks, particularly in patients with high triglyceride levels. The studies indicate that while omega-3s can effectively lower triglycerides and reduce certain cardiovascular disease outcomes, including fatal heart attacks, their overall benefit remains debated. Despite extensive research demonstrating some positive outcomes, many experts still question the magnitude of their effects on heart attack prevention. Improved guidance on omega-3 supplementation is still evolving as new evidence emerges.
Read More
9
DHA aids post-heart attack recovery
We explored the effects of docosahexaenoic acid (DHA) on heart attack recovery in rats. The study aimed to understand how DHA, alongside eicosapentaenoic acid (EPA), can influence heart failure following myocardial infarction (MI).
Using several groups of rats experiencing moderate heart issues, we evaluated how these omega-3 fatty acids impacted heart function. We found that both DHA and EPA effectively curtailed the hypertrophic response in heart cells. This response is a significant factor in heart failure, where heart tissue thickens and hardens.
Notably, both DHA and EPA inhibited the activity of a histone acetyltransferase called p300. This activity is linked to molecular changes that promote heart cell enlargement and fibrosis. In our analysis, we observed that these fatty acids not only preserved cardiac function but also prevented structural changes common after a heart attack.
Overall, we noted that DHA had a comparable protective effect to EPA, significantly improving heart health and reducing fibrosis in the heart tissue. As such, the findings suggest that incorporating DHA could be a heart-friendly choice post-heart attack.
Using several groups of rats experiencing moderate heart issues, we evaluated how these omega-3 fatty acids impacted heart function. We found that both DHA and EPA effectively curtailed the hypertrophic response in heart cells. This response is a significant factor in heart failure, where heart tissue thickens and hardens.
Notably, both DHA and EPA inhibited the activity of a histone acetyltransferase called p300. This activity is linked to molecular changes that promote heart cell enlargement and fibrosis. In our analysis, we observed that these fatty acids not only preserved cardiac function but also prevented structural changes common after a heart attack.
Overall, we noted that DHA had a comparable protective effect to EPA, significantly improving heart health and reducing fibrosis in the heart tissue. As such, the findings suggest that incorporating DHA could be a heart-friendly choice post-heart attack.
Read More
8
Omega-3 reduces heart attack risk
We explored the impact of omega-3 fatty acids on heart attack risk, focusing on African Americans. In a study analyzing data from the VITAL trial, we matched African American participants with non-Hispanic White individuals to simulate a randomized controlled trial.
Surprisingly, our findings indicated that omega-3 supplementation significantly decreased heart attack risk in African Americans but showed no benefit for non-Hispanic Whites. This highlights the importance of addressing racial differences in how individuals respond to omega-3 fish oil, urging further research in this area.
Surprisingly, our findings indicated that omega-3 supplementation significantly decreased heart attack risk in African Americans but showed no benefit for non-Hispanic Whites. This highlights the importance of addressing racial differences in how individuals respond to omega-3 fish oil, urging further research in this area.
Read More
Most Useful Reviews
7.5
Heart health improvement
1 people found this helpful
My dad has taken this excellent supplement for years, and it aids in maintaining his heart's healthy function. A great source of omega.
Read More
7.5
Vegan omega-3 benefits
1 people found this helpful
Deva Omega 3 DHA is a fantastic vegan addition to my diet. These tablets are easy to take and have noticeably improved my overall condition, which is important for eye, nervous system, and heart health. Plus, they are gluten-free and vegan-friendly. I recommend this product for anyone looking to maintain their health.
Read More
Medical Researches
SCIENTIFIC SCORE
Possibly Effective
Based on 30 Researches
7.2
- All Researches
9
Omega-3s' mixed effects on heart health
We examined the impact of omega-3 fatty acids, often found in fish oil, on heart attack risks, particularly in patients with high triglyceride levels. The studies indicate that while omega-3s can effectively lower triglycerides and reduce certain cardiovascular disease outcomes, including fatal heart attacks, their overall benefit remains debated. Despite extensive research demonstrating some positive outcomes, many experts still question the magnitude of their effects on heart attack prevention. Improved guidance on omega-3 supplementation is still evolving as new evidence emerges.
Read More
9
We explored whether icosapent ethyl (IPE), a refined omega-3 fatty acid, could lower heart attack risk among cigarette smokers. In the REDUCE-IT trial, over 8,000 statin-treated patients were randomly assigned to receive either IPE or a placebo for nearly five years.
Our findings showed that IPE significantly reduced cardiovascular events by 25%, especially for current and former smokers. Participants using IPE experienced heart attack rates similar to non-smokers, suggesting that IPE may help lessen cardiovascular risks associated with smoking.
Our findings showed that IPE significantly reduced cardiovascular events by 25%, especially for current and former smokers. Participants using IPE experienced heart attack rates similar to non-smokers, suggesting that IPE may help lessen cardiovascular risks associated with smoking.
Read More
9
DHA aids post-heart attack recovery
We explored the effects of docosahexaenoic acid (DHA) on heart attack recovery in rats. The study aimed to understand how DHA, alongside eicosapentaenoic acid (EPA), can influence heart failure following myocardial infarction (MI).
Using several groups of rats experiencing moderate heart issues, we evaluated how these omega-3 fatty acids impacted heart function. We found that both DHA and EPA effectively curtailed the hypertrophic response in heart cells. This response is a significant factor in heart failure, where heart tissue thickens and hardens.
Notably, both DHA and EPA inhibited the activity of a histone acetyltransferase called p300. This activity is linked to molecular changes that promote heart cell enlargement and fibrosis. In our analysis, we observed that these fatty acids not only preserved cardiac function but also prevented structural changes common after a heart attack.
Overall, we noted that DHA had a comparable protective effect to EPA, significantly improving heart health and reducing fibrosis in the heart tissue. As such, the findings suggest that incorporating DHA could be a heart-friendly choice post-heart attack.
Using several groups of rats experiencing moderate heart issues, we evaluated how these omega-3 fatty acids impacted heart function. We found that both DHA and EPA effectively curtailed the hypertrophic response in heart cells. This response is a significant factor in heart failure, where heart tissue thickens and hardens.
Notably, both DHA and EPA inhibited the activity of a histone acetyltransferase called p300. This activity is linked to molecular changes that promote heart cell enlargement and fibrosis. In our analysis, we observed that these fatty acids not only preserved cardiac function but also prevented structural changes common after a heart attack.
Overall, we noted that DHA had a comparable protective effect to EPA, significantly improving heart health and reducing fibrosis in the heart tissue. As such, the findings suggest that incorporating DHA could be a heart-friendly choice post-heart attack.
Read More
9
DHA supports heart recovery post-MI
We investigated how docosahexaenoic acid (DHA), a type of omega-3 fatty acid, influences recovery following a heart attack (MI) in the context of dietary fat intake. The study began by feeding mice with safflower oil (rich in omega-6 fatty acids) for 12 weeks, followed by DHA supplementation for another 8 weeks before inducing a heart attack.
Through this process, we observed that the early intake of safflower oil led to heightened inflammation, delaying the body’s ability to heal. However, when we supplemented with DHA, we noted a favorable shift. DHA increased the levels of specialized proresolving mediators (SPMs) that help the body resolve inflammation. These mediators seemed to counteract the negative effects of safflower oil by enhancing mechanisms in both the heart and kidneys critical for recovery post-MI.
Additionally, DHA contributed to an increase in resolving macrophages, which play a vital role in repairing the heart, and it also elevated T regulatory cells in the heart tissue during chronic heart failure. This might suggest that transitioning from a diet high in omega-6 fatty acids to one rich in omega-3s like DHA could improve outcomes after heart attacks.
Overall, while excessive safflower oil intake worsens inflammation and affects heart recovery, DHA promotes a healthier resolving phase, supporting better heart and kidney function in the aftermath of a heart attack.
Through this process, we observed that the early intake of safflower oil led to heightened inflammation, delaying the body’s ability to heal. However, when we supplemented with DHA, we noted a favorable shift. DHA increased the levels of specialized proresolving mediators (SPMs) that help the body resolve inflammation. These mediators seemed to counteract the negative effects of safflower oil by enhancing mechanisms in both the heart and kidneys critical for recovery post-MI.
Additionally, DHA contributed to an increase in resolving macrophages, which play a vital role in repairing the heart, and it also elevated T regulatory cells in the heart tissue during chronic heart failure. This might suggest that transitioning from a diet high in omega-6 fatty acids to one rich in omega-3s like DHA could improve outcomes after heart attacks.
Overall, while excessive safflower oil intake worsens inflammation and affects heart recovery, DHA promotes a healthier resolving phase, supporting better heart and kidney function in the aftermath of a heart attack.
Read More
9
We set out to explore how docosahexaenoic acid (DHA), a beneficial omega-3 fatty acid found in fish oil and seaweed, might play a role in heart health, particularly after a heart attack. Our findings stemmed from experiments on both isolated heart cells under low oxygen conditions and live mice experiencing myocardial infarction (MI), which is the medical term for a heart attack.
The results were promising. We observed that DHA not only improved cell survival in stressed heart cells but also minimized damage in mice following a heart attack. Specifically, we noted a reduction in heart injury and a boost in heart function, highlighting DHA's potential as a protective agent.
Importantly, we found that DHA enhances autophagy—a natural process that cleans out damaged cells—by activating specific signaling pathways in the body. We established that in both our test models, the presence of DHA led to less cell death and richer heart function recovery. However, when we inhibited the autophagy process in experiments, the protective advantages of DHA were lost, underscoring its reliance on this cell-cleaning mechanism.
Our study indicates that DHA may serve as a valuable aid in healing the heart after a heart attack by promoting processes that protect against cell damage. Balancing scientific insight with real-world implications offers a promising avenue for heart health strategies, especially for those recovering from myocardial infarction.
The results were promising. We observed that DHA not only improved cell survival in stressed heart cells but also minimized damage in mice following a heart attack. Specifically, we noted a reduction in heart injury and a boost in heart function, highlighting DHA's potential as a protective agent.
Importantly, we found that DHA enhances autophagy—a natural process that cleans out damaged cells—by activating specific signaling pathways in the body. We established that in both our test models, the presence of DHA led to less cell death and richer heart function recovery. However, when we inhibited the autophagy process in experiments, the protective advantages of DHA were lost, underscoring its reliance on this cell-cleaning mechanism.
Our study indicates that DHA may serve as a valuable aid in healing the heart after a heart attack by promoting processes that protect against cell damage. Balancing scientific insight with real-world implications offers a promising avenue for heart health strategies, especially for those recovering from myocardial infarction.
Read More
User Reviews
USERS' SCORE
Good
Based on 2 Reviews
8.3
- All Reviews
- Positive Reviews
- Negative Reviews
7.5
Heart health improvement
1 people found this helpful
My dad has taken this excellent supplement for years, and it aids in maintaining his heart's healthy function. A great source of omega.
Read More
7.5
Vegan omega-3 benefits
1 people found this helpful
Deva Omega 3 DHA is a fantastic vegan addition to my diet. These tablets are easy to take and have noticeably improved my overall condition, which is important for eye, nervous system, and heart health. Plus, they are gluten-free and vegan-friendly. I recommend this product for anyone looking to maintain their health.
Read More
Frequently Asked Questions
No FAQs are available for this product and symptom.
References
- Aggarwal R, Bhatt DL, Steg PG, Miller M, Brinton EA, et al. Cardiovascular Outcomes With Icosapent Ethyl by Baseline Low-Density Lipoprotein Cholesterol: A Secondary Analysis of the REDUCE-IT Randomized Trial. J Am Heart Assoc. 2025;14:e038656. doi:10.1161/JAHA.124.038656
- Sun S, Hara A, Johnstone L, Hallmark B, Watkins JC, et al. Optimal Pair Matching Combined with Machine Learning Predicts a Significant Reduction in Myocardial Infarction Risk in African Americans Following Omega-3 Fatty Acid Supplementation. Nutrients. 2024;16. doi:10.3390/nu16172933
- Ahmadi M, Askari VR, Shahri B, Mousavi Noghab SM, Jarahi L, et al. Omega-3 fatty acids effectively mitigate high-sensitivity C-reactive protein (hs-CRP) biomarker of inflammation in acute myocardial infarction patients: a randomized, double-blind, placebo-controlled clinical trial. Naunyn Schmiedebergs Arch Pharmacol. 2025;398:881. doi:10.1007/s00210-024-03330-1
- Burger PM, Bhatt DL, Dorresteijn JAN, Koudstaal S, Mosterd A, et al. Effects of icosapent ethyl according to baseline residual risk in patients with atherosclerotic cardiovascular disease: results from REDUCE-IT. Eur Heart J Cardiovasc Pharmacother. 2024;10:488. doi:10.1093/ehjcvp/pvae030
- Bernhard B, Heydari B, Abdullah S, Francis SA, Lumish H, et al. Effect of six month's treatment with omega-3 acid ethyl esters on long-term outcomes after acute myocardial infarction: The OMEGA-REMODEL randomized clinical trial. Int J Cardiol. 2024;399:131698. doi:10.1016/j.ijcard.2023.131698
- Irfan A, Haider SH, Nasir A, Larik MO, Naz T. Assessing the Efficacy of Omega-3 Fatty Acids + Statins vs. Statins Only on Cardiovascular Outcomes: A Systematic Review and Meta-Analysis of 40,991 Patients. Curr Probl Cardiol. 2024;49:102245. doi:10.1016/j.cpcardiol.2023.102245
- Ogata S, Manson JE, Kang JH, Buring JE, Lee IM, et al. Marine n-3 Fatty Acids and Prevention of Cardiovascular Disease: A Novel Analysis of the VITAL Trial Using Win Ratio and Hierarchical Composite Outcomes. Nutrients. 2023;15. doi:10.3390/nu15194235
- Jin D, Trichia E, Islam N, Lewington S, Lacey B. Associations of circulating fatty acids with incident coronary heart disease: a prospective study of 89,242 individuals in UK Biobank. BMC Cardiovasc Disord. 2023;23:365. doi:10.1186/s12872-023-03394-6
- Lyytinen AT, Yesmean M, Manninen S, Lankinen M, Bhalke M, et al. Fatty fish consumption reduces lipophilic index in erythrocyte membranes and serum phospholipids. Nutr Metab Cardiovasc Dis. 2023;33:1453. doi:10.1016/j.numecd.2023.04.011
- Chiusolo S, Bork CS, Gentile F, Lundbye-Christensen S, Harris WS, et al. Adipose tissue n-3/n-6 fatty acids ratios versus n-3 fatty acids fractions as predictors of myocardial infarction. Am Heart J. 2023;262:38. doi:10.1016/j.ahj.2023.03.019
- Kobara M, Shiraishi T, Noda K, Toba H, Nakata T. Eicosapentaenoic Acid Preserves Mitochondrial Quality and Attenuates Cardiac Remodeling After Myocardial Infarction in Rats. J Cardiovasc Transl Res. 2023;16:816. doi:10.1007/s12265-023-10363-z
- Rodriguez D, Lavie CJ, Elagizi A, Milani RV. Update on Omega-3 Polyunsaturated Fatty Acids on Cardiovascular Health. Nutrients. 2022;14. doi:10.3390/nu14235146
- Bassuk SS, Manson JE. Marine omega-3 fatty acid supplementation and prevention of cardiovascular disease: update on the randomized trial evidence. Cardiovasc Res. 2023;119:1297. doi:10.1093/cvr/cvac172
- Nishizaki Y, Miyauchi K, Iwata H, Inoue T, Hirayama A, et al. Study protocol and baseline characteristics of Randomized trial for Evaluation in Secondary Prevention Efficacy of Combination Therapy-Statin and Eicosapentaenoic Acid: RESPECT-EPA, the combination of a randomized control trial and an observational biomarker study. Am Heart J. 2023;257:1. doi:10.1016/j.ahj.2022.11.008
- Miller M, Bhatt DL, Steg PG, Brinton EA, Jacobson TA, et al. Potential effects of icosapent ethyl on cardiovascular outcomes in cigarette smokers: REDUCE-IT smoking. Eur Heart J Cardiovasc Pharmacother. 2023;9:129. doi:10.1093/ehjcvp/pvac045
- Yokoyama Y, Kuno T, Morita SX, Slipczuk L, Takagi H, et al. Eicosapentaenoic Acid for Cardiovascular Events Reduction- Systematic Review and Network Meta-Analysis of Randomized Controlled Trials. J Cardiol. 2022;80:416. doi:10.1016/j.jjcc.2022.07.008
- Hamaya R, Cook NR, Sesso HD, Buring JE, Manson JE. A Bayesian Analysis of the VITAL Trial: Effects of Omega-3 Fatty Acid Supplementation on Cardiovascular Events. Am J Clin Nutr. 2025. doi:10.1016/j.ajcnut.2025.02.028
- Dinu M, Sofi F, Lotti S, Colombini B, Mattioli AV, et al. Effects of omega-3 fatty acids on coronary revascularization and cardiovascular events: a meta-analysis. Eur J Prev Cardiol. 2024;31:1863. doi:10.1093/eurjpc/zwae184
- Le VT, Knight S, Watrous JD, Najhawan M, Dao K, et al. Higher docosahexaenoic acid levels lower the protective impact of eicosapentaenoic acid on long-term major cardiovascular events. Front Cardiovasc Med. 2023;10:1229130. doi:10.3389/fcvm.2023.1229130
- Luo X, Liu M, Wang S, Chen Y, Bao X, et al. Combining metabolomics and OCT to reveal plasma metabolic profiling and biomarkers of plaque erosion and plaque rupture in STEMI patients. Int J Cardiol. 2023;390:131223. doi:10.1016/j.ijcard.2023.131223
- Myhre PL, Berge T, Kalstad AA, Tveit SH, Laake K, et al. Omega-3 fatty acid supplements and risk of atrial fibrillation and 'micro-atrial fibrillation': A secondary analysis from the OMEMI trial. Clin Nutr. 2023;42:1657. doi:10.1016/j.clnu.2023.07.002
- Bork CS, Lundbye-Christensen S, Venø SK, Lasota AN, Tjønneland A, et al. Intake of marine and plant-derived n-3 fatty acids and development of atherosclerotic cardiovascular disease in the Danish Diet, Cancer and Health cohort. Eur J Nutr. 2023;62:1389. doi:10.1007/s00394-022-03081-w
- Park GH, Cho JH, Lee D, Kim Y. Association between Seafood Intake and Cardiovascular Disease in South Korean Adults: A Community-Based Prospective Cohort Study. Nutrients. 2022;14. doi:10.3390/nu14224864
- Alfaddagh A, Kapoor K, Dardari ZA, Bhatt DL, Budoff MJ, et al. Omega-3 fatty acids, subclinical atherosclerosis, and cardiovascular events: Implications for primary prevention. Atherosclerosis. 2022;353:11. doi:10.1016/j.atherosclerosis.2022.06.1018
- Sunagawa Y, Katayama A, Funamoto M, Shimizu K, Shimizu S, et al. The polyunsaturated fatty acids, EPA and DHA, ameliorate myocardial infarction-induced heart failure by inhibiting p300-HAT activity in rats. J Nutr Biochem. 2022;106:109031. doi:10.1016/j.jnutbio.2022.109031
- Halade GV, Kain V, De La Rosa X, Lindsey ML. Metabolic transformation of fat in obesity determines the inflammation resolving capacity of splenocardiac and cardiorenal networks in heart failure. Am J Physiol Heart Circ Physiol. 2022;322:H953. doi:10.1152/ajpheart.00684.2021
- Shi Y, Li H, Wu T, Wang Q, Zhu Q, et al. Docosahexaenoic Acid-Enhanced Autophagic Flux Improves Cardiac Dysfunction after Myocardial Infarction by Targeting the AMPK/mTOR Signaling Pathway. Oxid Med Cell Longev. 2022;2022:1509421. doi:10.1155/2022/1509421
- Wang CP, Lee CC, Wu DY, Chen SY, Lee TM. Differential effects of EPA and DHA on PPARγ-mediated sympathetic innervation in infarcted rat hearts by GPR120-dependent and -independent mechanisms. J Nutr Biochem. 2022;103:108950. doi:10.1016/j.jnutbio.2022.108950
- Myhre PL, Kalstad AA, Tveit SH, Laake K, Schmidt EB, et al. Changes in eicosapentaenoic acid and docosahexaenoic acid and risk of cardiovascular events and atrial fibrillation: A secondary analysis of the OMEMI trial. J Intern Med. 2022;291:637. doi:10.1111/joim.13442
- Pertiwi K, Küpers LK, de Goede J, Zock PL, Kromhout D, et al. Dietary and Circulating Long-Chain Omega-3 Polyunsaturated Fatty Acids and Mortality Risk After Myocardial Infarction: A Long-Term Follow-Up of the Alpha Omega Cohort. J Am Heart Assoc. 2021;10:e022617. doi:10.1161/JAHA.121.022617
